Genome # 11
- ANON2; BULN2
- Summary
- The protein encoded by this gene is a member of the nerve
growth factor family. It is induced by cortical neurons, and is
necessary for survival of striatal neurons in the brain. Expression of
this gene is reduced in both Alzheimer's and Huntington disease
patients. This gene may play a role in the regulation of stress response
and in the biology of mood disorders. Multiple transcript variants
encoding distinct isoforms have been described for this gene. [provided
by RefSeq, Jan 2009]
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